Literature summary for 4.1.1.20 extracted from

Kelland, J.C.; Arnold, L.D.; Palcic, M.M.; Pickard, M.A.; Vederas, J.C.
Analogs of diaminopimelic acid as inhibitors of meso-diaminopimelate decarboxylase from Bacillus sphaericus and wheat germ (1986), J. Biol. Chem., 261, 13216-13223.

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Inhibitors

Inhibitors	Comment	Organism	Structure
diaminoheptanedioic acid	analogs	Lysinibacillus sphaericus
additional information	various substrate analogs	Lysinibacillus sphaericus
additional information	various substrate analogs	Triticum sp.
N-Hydroxydiaminoheptanedioate	Ki: 0.91 mM	Lysinibacillus sphaericus
N-Hydroxydiaminoheptanedioate	Ki: 0.71 mM	Triticum sp.

Organism

Organism	UniProt	Comment	Textmining
Lysinibacillus sphaericus	-	-	-
Triticum sp.	-	wheat	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
germ	-	Lysinibacillus sphaericus	-
germ	-	Triticum sp.	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
meso-2,6-Diaminoheptanedioate	-	Lysinibacillus sphaericus	L-Lysine + CO2	-	?
meso-2,6-Diaminoheptanedioate	-	Triticum sp.	L-Lysine + CO2	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.91	-	N-Hydroxydiaminoheptanedioate	-	Lysinibacillus sphaericus

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Release 2023.1 (January 2023)