Activating Compound | Comment | Organism | Structure |
---|---|---|---|
dithiothreitol | absolute requirement | Trypanosoma cruzi | |
DL-alpha-difluoromethylornithine | activates | Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DL-alpha-difluoromethylarginine | - |
Trypanosoma cruzi |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5 | - |
L-Arg | double reciprocal plot is biphasic with a Km-value of 10 mM at higher concentrations of L-Arg | Trypanosoma cruzi |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | absolute requirement | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Trypanosoma cruzi RA | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epimastigote | enzyme activity is only present in the early stage of the parasite exponential growth, between 4 and 23 h of cultivation in presence of Arg, with a maximum at 14 h and disappears completely at the mid logarithmic phase. It is never detected during the stationary phase | Trypanosoma cruzi | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | - |
Trypanosoma cruzi | agmatine + CO2 | - |
? | |
L-arginine | - |
Trypanosoma cruzi RA | agmatine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADC | - |
Trypanosoma cruzi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.9 | - |
- |
Trypanosoma cruzi |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
7.9 | - |
maximal activity | Trypanosoma cruzi |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | absolute requirement | Trypanosoma cruzi |