Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Omeprazole | 50% inhibition at 0.016 mg/ml for enzyme from metronidazole-resistant strain or from cells grown under iron-limited conditions, little effect on enzyme from metronidazole-susceptible strain | Tritrichomonas suis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.62 | - |
pyruvate | pH 6.2, 25°C | Tritrichomonas suis | |
1.25 | - |
pyruvate | pH 6.2, 25°C, presence of 0.1 M NaCl | Tritrichomonas suis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Tritrichomonas suis | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
4 * 60000, SDS-PAGE | Tritrichomonas suis |
240000 | - |
gel filtration | Tritrichomonas suis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tritrichomonas suis | - |
activity in metronidazole- or iron-restricted cells is 20-30 times higher than in metronidazole-sensitive strain | - |
Purification (Comment) | Organism |
---|---|
- |
Tritrichomonas suis |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5.7 | - |
pH 6.2, 25°C, metronidazole-resistant strain | Tritrichomonas suis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | - |
Tritrichomonas suis | acetaldehyde + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 60000, SDS-PAGE | Tritrichomonas suis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.75 | 6.5 | - |
Tritrichomonas suis |