Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NRX4 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation | Homo sapiens | - |
LX-2 cell | colocalization of the enzyme (PHP14) with Arp3 and F-actin at the leading edge of migrating cells. PHP14 is recruited to the actin remodeling sites in parallel with Arp3 during lamellipodia formation | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
PHP14 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | PHP14 knockdown impairs Arp3 localization at the leading edge of lamellipodia, as well as lamellipodia formation | Homo sapiens |
physiological function | role for PHP14 in the dynamic regulation of the actin cytoskeleton and cell migration | Homo sapiens |