Protein Variants | Comment | Organism |
---|---|---|
H53A | inactive | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[ATP-citrate lyase]-N-phospho-L-histidine + H2O | Mus musculus | - |
[ATP-citrate lyase]-L-histidine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SN-56 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[ATP-citrate lyase]-N-phospho-L-histidine + H2O | - |
Mus musculus | [ATP-citrate lyase]-L-histidine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PHP | - |
Mus musculus |
protein histidine phosphatase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme downregulation does not induce cell death, but significantly increases the acetylcholine content in SN-56 cells | Mus musculus |
metabolism | the enzyme downregulates the activity of ATP-citrate lyase by dephosphorylation | Mus musculus |
physiological function | enzyme overexpression reduces the acetylcholine level and induces cell death | Mus musculus |