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Literature summary for 3.8.1.2 extracted from

  • Onda, M; Motosugi, K.; Nakajima, H.
    A new approach for enzymatic synthesis of D-3-chlorolactic acd from racemic 2,3-dichloropropionic acid by halo acid dehalogenase (1990), Agric. Biol. Chem., 54, 3031-3033.
No PubMed abstract available
Search for more literature for 3.8.1.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-2-haloalkanoic acid + H2O Pseudomonas putida
-
 D-2-hydroxyalkanoic acid + halide
-
 ?
L-2-haloalkanoic acid + H2O Rhizobium sp.
-
 D-2-hydroxyalkanoic acid + halide
-
 ?
L-2-haloalkanoic acid + H2O Pseudomonas putida No. 109
-
 D-2-hydroxyalkanoic acid + halide
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
-
 No. 109
-
Pseudomonas putida No. 109
-
 No. 109
-
Rhizobium sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-2-haloacid + H2O
-
 Pseudomonas putida (R)-2-hydroxyacid + halide
-
 ?
(S)-2-haloacid + H2O
-
 Rhizobium sp. (R)-2-hydroxyacid + halide
-
 ?
(S)-2-haloacid + H2O
-
 Pseudomonas putida No. 109 (R)-2-hydroxyacid + halide
-
 ?
2,2-dichloropropionic acid + H2O
-
 Rhizobium sp. propionate + HCl
-
 ?
2,3-dibromopropionate + H2O
-
 Pseudomonas putida ?
-
 ?
2,3-dibromopropionate + H2O
-
 Pseudomonas putida No. 109 ?
-
 ?
2,3-dichloropropionic acid + H2O
-
 Pseudomonas putida 3-chlorlactic acid + HCl
-
 ?
2,3-dichloropropionic acid + H2O
-
 Pseudomonas putida No. 109 3-chlorlactic acid + HCl
-
 ?
L-2-chloropropionate + H2O
-
 Pseudomonas putida D-lactate + HCl
-
 ?
L-2-chloropropionate + H2O
-
 Rhizobium sp. D-lactate + HCl
-
 ?
L-2-chloropropionate + H2O
-
 Pseudomonas putida No. 109 D-lactate + HCl
-
 ?
L-2-haloalkanoic acid + H2O
-
 Pseudomonas putida D-2-hydroxyalkanoic acid + halide
-
 ?
L-2-haloalkanoic acid + H2O
-
 Rhizobium sp. D-2-hydroxyalkanoic acid + halide
-
 ?
L-2-haloalkanoic acid + H2O
-
 Pseudomonas putida No. 109 D-2-hydroxyalkanoic acid + halide
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
7 9 the enzyme reaction is retarded below pH 6.0 and the reaction is spontaneously over pH 9.0 Pseudomonas putida