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Literature summary for 3.7.1.4 extracted from

  • Bulhoes, A.C.; Goldani, H.A.; Oliveira, F.S.; Matte, U.S.; Mazzuca, R.B.; Silveira, T.R.
    Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia (2007), Braz. J. Med. Biol. Res., 40, 1441-1446.
    View publication on PubMed
Search for more literature for 3.7.1.4

Application

Application Comment Organism
medicine adult-type hypolactasia is characterized by a fall of lactase activity levels to 5 - 10% of birth levels occuring during childhood and adolescence Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information the mutations C/T-13910 and G/A-22018 of the lactase-phlorizin hydrolase gene are correlated with lactose absorption Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phloretin + H2O Homo sapiens
-
 phloretate + phloroglucinol
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09848
-
-

Source Tissue

Source Tissue Comment Organism Textmining
small intestine intestinal villus Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lactose + H2O
-
 Homo sapiens D-glucose + D-galactose
-
 ?
phloretin + H2O
-
 Homo sapiens phloretate + phloroglucinol
-
 ?

Synonyms

Synonyms Comment Organism
lactase-phlorizin hydrolase
-
 Homo sapiens
LCT
-
 Homo sapiens
LPH
-
 Homo sapiens
phloretin hydrolase
-
 Homo sapiens