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Literature summary for 3.7.1.4 extracted from
- Dietary sucrose enhances intestinal lactase gene expression in euthyroid rats (2006), J. Nutr. Sci. Vitaminol., 52, 347-351.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| sucrose | is capable of enhancing lactase gene expression in starved rats when they have a sustainable thyroid hormone level | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| thyroid hormone | LPH mRNA level and lactase activity repressed by the injection of thyroid hormones during starvation | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | - |
Rattus norvegicus | - |
| jejunum | 85% reduced LPH mRNA level in rats fed a low starch diet as compared to rats fed a high starch diet | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactose + H2O | 66% reduced activity towards the substrate in rats fed a low starch diet as compared to rats fed a high starch diet | Rattus norvegicus | ? | - |
? | |
| sucrose + H2O | 87% reduced activity towards the substrate in rats fed a low starch diet as compared to rats fed a high starch diet | Rattus norvegicus | D-fructose + D-glucose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lactase/phlorizin hydrolase | - |
Rattus norvegicus |
| LPH | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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