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Literature summary for 3.7.1.4 extracted from

  • Bodlaj, G.; Stoecher, M.; Hufnagl, P.; Hubmann, R.; Biesenbach, G.; Stekel, H.; Berg, J.
    Genotyping of the lactase-phlorizin hydrolase -13910 polymorphism by lightCycler PCR and implications for the diagnosis of lactose intolerance (2006), Clin. Chem., 52, 148-151.
    View publication on PubMed
Search for more literature for 3.7.1.4

Application

Application Comment Organism
medicine rapid genotyping assay for LPH-13910 polymorphism based on real-time PCR, which may assist in differentiating patients with primary hypolactasia from those with secondary hypolactasia and lactose intolerance Homo sapiens
medicine hypolactasia seems to be strongly corretated with genotype C/C of the genetic variant C->T-13910 upstream of the lactase-phlorizin hydrolase gene Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information hypolactasia seems to be strongly corretated with genotype C/C of the genetic variant C->T-13910 upstream of the lactase-phlorizin hydrolase gene Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phloretin + H2O Homo sapiens
-
 phloretate + phloroglucinol
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lactose + H2O
-
 Homo sapiens D-glucose + D-galactose
-
 ?
lactose + H2O
-
 Homo sapiens glucose + galactose
-
 ?
phloretin + H2O
-
 Homo sapiens phloretate + phloroglucinol
-
 ?

Synonyms

Synonyms Comment Organism
lactase-phlorizin hydrolase
-
 Homo sapiens
LPH
-
 Homo sapiens
phloretin hydrolase
-
 Homo sapiens