Application | Comment | Organism |
---|---|---|
medicine | NAD+ biosynthesis | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.013 | - |
L-3-hydroxykynurenine | - |
Rattus norvegicus | |
0.4 | - |
L-kynurenine | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
2 * 55000, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-L-kynurenine + H2O | Rattus norvegicus | - |
3-hydroxyanthranilate + L-Ala | - |
? | |
L-kynurenine + H2O | Rattus norvegicus | - |
anthranilate + L-alanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.25 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-L-kynurenine + H2O | - |
Rattus norvegicus | 3-hydroxyanthranilate + L-alanine | - |
? | |
3-hydroxy-L-kynurenine + H2O | - |
Rattus norvegicus | 3-hydroxyanthranilate + L-Ala | - |
? | |
L-kynurenine + H2O | - |
Rattus norvegicus | anthranilate + L-alanine | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 55000, SDS-PAGE | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |