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Literature summary for 3.7.1.3 extracted from

  • Shibata, Y.; Takeuchi, F.; Tsubouchi, R.; Haneda, M.; Ohta, T.; Nakatsuka, M.; Nisimoto, Y.; Tamai, T.; Nomura, S.; Fujimoto, H.; Sakata, M.; Maesaki, T.; Goda, K.
    On kynureninase activity (1991), Adv. Exp. Med. Biol., 294, 523-526.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
p-hydroxyphenylpyruvate 5 mM Rattus norvegicus
phenylpyruvate 1 mM Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-L-kynurenine + H2O Rattus norvegicus
-
3-hydroxyanthranilate + L-Ala
-
?
L-kynurenine + H2O Rattus norvegicus
-
anthranilate + L-alanine
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-L-kynurenine + H2O
-
Rattus norvegicus 3-hydroxyanthranilate + L-alanine
-
?
3-hydroxy-L-kynurenine + H2O
-
Rattus norvegicus 3-hydroxyanthranilate + L-Ala
-
?
L-kynurenine + H2O
-
Rattus norvegicus anthranilate + L-alanine
-
?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Rattus norvegicus