Any feedback?
Literature summary for 3.7.1.3 extracted from
- Kynureninase from Neurospora: Purification and properties (1953), J. Biol. Chem., 205, 699-707.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-hydroxy-DL-kynurenine | - |
Neurospora crassa |  |
| KCN | 1 mM | Neurospora crassa | |
| kynurenine | - |
Neurospora crassa | |
| N'-formyl-L-kynurenine | - |
Neurospora crassa | |
| NaHSO3 | 1 mM | Neurospora crassa | |
| NH2OH | 0.1 mM | Neurospora crassa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.003 | - |
3-hydroxy-L-kynurenine | - |
Neurospora crassa | |
| 0.006 | - |
kynurenine | - |
Neurospora crassa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Neurospora crassa | |
| Mg2+ | - |
Neurospora crassa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-hydroxy-L-kynurenine + H2O | Neurospora crassa | - |
3-hydroxyanthranilate + L-Ala | - |
? | |
| L-kynurenine + H2O | Neurospora crassa | - |
anthranilate + L-alanine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Neurospora crassa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-hydroxy-L-kynurenine + H2O | - |
Neurospora crassa | 3-hydroxyanthranilate + L-alanine | - |
? | |
| 3-hydroxy-L-kynurenine + H2O | - |
Neurospora crassa | 3-hydroxyanthranilate + L-Ala | - |
? | |
| L-kynurenine + H2O | - |
Neurospora crassa | anthranilate + L-alanine | - |
? | |
| N-formyl-L-kynurenine + H2O | - |
Neurospora crassa | N-formylanthranilate + L-alanine | - |
? | |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | 37 | - |
Neurospora crassa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.1 | - |
- |
Neurospora crassa |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
- |
Neurospora crassa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Neurospora crassa | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
