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Literature summary for 3.7.1.2 extracted from
- Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage (2005), Biochem. J., 388, 721-730.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Mus musculus |  |
| Mg2+ | stabilizes the beta-roll that constitutes the active site of the enzyme | Mus musculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 46000 | - |
2 * 46000, method not mentioned | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-fumarylacetoacetate + H2O | - |
Mus musculus | acetoacetate + fumarate | - |
? | |
| 4-fumarylacetoacetate + H2O | - |
Bos taurus | acetoacetate + fumarate | - |
? | |
| acetylpyruvate + H2O | - |
Bos taurus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 46000, method not mentioned | Mus musculus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FAH | - |
Mus musculus |
| FAH | - |
Bos taurus |
| fumarylacetoacetate hydrolase | - |
Mus musculus |
| fumarylacetoacetate hydrolase | - |
Bos taurus |
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Release 2023.1 (January 2023)
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