Any feedback?
Literature summary for 3.6.5.6 extracted from
- Structural model of a complex between the heterotrimeric G protein, Gsalpha, and tubulin (2008), Biochim. Biophys. Acta, 1783, 964-973.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Gsalpha | Gsalpha facilitates GTP hydrolysis on tubulin, which leads to microtubule depolymerization by increased GTPase activation on tubulin | Ovis aries |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Ovis aries | - |
GDP + phosphate | - |
ir |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ovis aries | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ovine brain tubulin is prepared from freshly-killed animals using phosphocellulose chromatography | Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Ovis aries | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Ovis aries | GDP + phosphate | - |
ir | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterodimer | consists of an alpha and beta monomer | Ovis aries |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| tubulin GTPase | - |
Ovis aries |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
