Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
GTP + H2O = GDP + phosphate | mechanism | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
additional information | GTP hydrolysis occurs at a single exchangeable GTP-binding site which is at the interface between head-to-tail arranged heterodimer enzyme | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | proteins Op18, RB3 and SCG10 of the oncoprotein18/stathmin family bind and stimulate enzyme at a low and indistinguishable rate of GTP hydrolysis, complex of enzyme and proteins may prevent futile cycles of GTP hydrolysis | Homo sapiens |