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Literature summary for 3.6.5.5 extracted from

  • Breinich, M.S.; Ferguson, D.J.; Foth, B.J.; van Dooren, G.G.; Lebrun, M.; Quon, D.V.; Striepen, B.; Bradley, P.J.; Frischknecht, F.; Carruthers, V.B.; Meissner, M.
    A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii (2009), Curr. Biol., 19, 277-286.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm DrpB accumulates in a cytoplasmic region close to the Golgi that breaks up during replication and reforms after assembly of the daughter cells Toxoplasma gondii 5737
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Toxoplasma gondii DrpB is required during replication to generate vesicles for the regulated secretory pathway that form the unique secretory organelles, DrpB is required for the transport of secretory proteins ?
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?

Organic Solvent Stability

Organic Solvent Comment Organism
Triton X-100 DrpB is almost completely insoluble and can only be partially solubilized by detergent extraction (2% Triton X-100) Toxoplasma gondii

Organism

Organism UniProt Comment Textmining
Toxoplasma gondii
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-
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Source Tissue

Source Tissue Comment Organism Textmining
tachyzoite
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Toxoplasma gondii
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
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Toxoplasma gondii GDP + phosphate
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?
additional information DrpB is required during replication to generate vesicles for the regulated secretory pathway that form the unique secretory organelles, DrpB is required for the transport of secretory proteins Toxoplasma gondii ?
-
?

Synonyms

Synonyms Comment Organism
DrpB
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Toxoplasma gondii
dynamin-related protein B
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Toxoplasma gondii