Cloned (Comment) | Organism |
---|---|
the vectors pcDNA3.1 and pADT3T7tet are used, recombinant adenoviruses are produced in HEK293-Cre cells | Homo sapiens |
the vectors pcDNA3.1 and pADT3T7tet are used, recombinant adenoviruses are produced in HEK293-Cre cells | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
Dyn2DELTAPRD | truncation mutant lacking the C-terminal proline-arginine-rich domain, PRD | Rattus norvegicus |
Dyn2I684K | point mutation to render Dyn2 defective in oligomerization and self-assembly | Rattus norvegicus |
Dyn2I684KDELTAPRD | point mutation to render Dyn2 defective in oligomerization and self-assembly | Rattus norvegicus |
Dyn2S45N | point mutation to render Dyn2 defective in GTP binding | Rattus norvegicus |
Dyn2S45N/I684K | point mutations to render Dyn2 defective in GTP binding and in oligomerization and self-assembly | Rattus norvegicus |
DynII690K | point mutation to render Dyn1 defective in oligomerization and self-assembly | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
ir | |
GTP + H2O | Rattus norvegicus | - |
GDP + phosphate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
ir | |
GTP + H2O | - |
Rattus norvegicus | GDP + phosphate | - |
ir |
Subunits | Comment | Organism |
---|---|---|
heterotetramer | Dyn1 can interfere with Dyn2 or Dyn2 mutants, Dyn2-Dyn1, Dyn2S45N-Dyn1 and Dyn2-Dyn1I690K heteromers are formed | Homo sapiens |
heterotetramer | Dyn2 can interfere with Dyn2 mutants or Dyn1, Dyn2-Dyn1, Dyn2S45N-Dyn1 and Dyn2-Dyn1I690K heteromers are formed | Rattus norvegicus |
homotetramer | - |
Homo sapiens |
homotetramer | - |
Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
dynamin GTPase | - |
Homo sapiens |
dynamin GTPase | - |
Rattus norvegicus |
dynamin-1 | human dynamin-1aa splice variant | Homo sapiens |
dynamin-2 | rat dynamin-2ba splice variant | Rattus norvegicus |