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Literature summary for 3.6.5.5 extracted from

  • Thompson, H.M.; Skop, A.R.; Euteneuer, U.; Meyer, B.J.; McNiven, M.A.
    The large GTPase dynamin associates with the spindle midzone and is required for cytokinesis (2002), Curr. Biol., 12, 2111-2117.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information dyn-1 temperature-sensitive mutant dyn-1(ky51) Caenorhabditis elegans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane dynamin localizes to newly formed cleavage furrow membranes and accumulates at the midbody of dividing embryos Caenorhabditis elegans 16020
-
spindle mitotic, midzone Caenorhabditis elegans 5819
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Caenorhabditis elegans the large GTPase dynamin is involved in membrane tubulation and vesiculation, it associates with the spindle midzone and is required for cytokinesis GDP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
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Dyn-1, wild-type N2 strain, mutant strain dyn-1(ky51)
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo dynamin localizes to newly formed cleavage furrow membranes and accumulates at the midbody of dividing embryos Caenorhabditis elegans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
Caenorhabditis elegans GDP + phosphate
-
?
GTP + H2O the large GTPase dynamin is involved in membrane tubulation and vesiculation, it associates with the spindle midzone and is required for cytokinesis Caenorhabditis elegans GDP + phosphate
-
?

Synonyms

Synonyms Comment Organism
Dyn-1
-
Caenorhabditis elegans