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Literature summary for 3.6.5.5 extracted from

  • Warnock, D.E.; Schmid, S.L.
    Dynamin GTPase, a force-generating molecular switch (1996), Bioessays, 18, 885-893.
    View publication on PubMed
Search for more literature for 3.6.5.5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Homo sapiens regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force GDP + phosphate
-
 ?
GTP + H2O Rattus norvegicus regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Drosophila sp. (in: flies) GDP + phosphate
-
 ?
GTP + H2O
-
 Homo sapiens GDP + phosphate
-
 ?
GTP + H2O
-
 Rattus norvegicus GDP + phosphate
-
 ?
GTP + H2O regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force Homo sapiens GDP + phosphate
-
 ?
GTP + H2O regulates late events in clathrin-coated vescicle formation, GTP hydrolysis is required for vesicle detachment, a concerted conformational change resulting from coordinated GTP hydrolysis by the dynamin oligomer might by sufficient to generate force Rattus norvegicus GDP + phosphate
-
 ?