Literature summary for 3.6.5.4 extracted from

Abe, K.; Hattori, T.; Isobe, T.; Kitagawa, K.; Oda, T.; Uchida, C.; Kitagawa, M.
Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit (2008), Biomed. Res., 29, 53-60.

Search for more literature for 3.6.5.4

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21-CodonPlus(DE3) cells and in COS-1 cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Homo sapiens	5783	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
glutathione Sepharose column chromatography	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the RING-H2 type E3 ubiquitin ligase Pirh2 (p53-inducible protein with RING-H2 domain) poly-ubiquitylates the signal recognition particle receptor beta subunit in an intact RING finger domain-dependent manner in vivo and in vitro, Pirh2 preferentially utilizes lysine residues 6 and 29 of the ubiquitin to mediate the formation of polyubiquitin chains on the signal recognition particle receptor beta subunit	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
signal recognition particle receptor beta subunit	-	Homo sapiens
SRbeta	-	Homo sapiens

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Release 2023.1 (January 2023)