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Literature summary for 3.6.5.3 extracted from

  • Shin, B.S.; Kim, J.R.; Acker, M.G.; Maher, K.N.; Lorsch, J.R.; Dever, T.E.
    rRNA suppressor of a eukaryotic translation initiation factor 5B/initiation factor 2 mutant reveals a binding site for translational GTPases on the small ribosomal subunit (2009), Mol. Cell. Biol., 29, 808-821.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
H480I impair of GTP hydrolysis and yeast cell growth Saccharomyces cerevisiae
H480I/A709V double mutant, faster yeast cell growth Saccharomyces cerevisiae
H480I/F643R double mutant, suppression of H480I-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
H480I/G642F double mutant, suppression of H480I-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
H480I/I634G double mutant, suppression of H480I-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
H480I/V637A double mutant, suppression of H480I-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
H480I/V637G double mutant, suppression of H480I-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
T439A slow-growth phenotype Saccharomyces cerevisiae
T439A/F643R double mutant, suppression of T439A-mutant mediated slow yeast cell growth Saccharomyces cerevisiae
T439A/V637G double mutant, suppression of T439A-mutant mediated slow yeast cell growth Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae NOY891
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
Saccharomyces cerevisiae GDP + phosphate
-
?
GTP + H2O
-
Saccharomyces cerevisiae NOY891 GDP + phosphate
-
?

Synonyms

Synonyms Comment Organism
eIF5B
-
Saccharomyces cerevisiae
ribosome-dependent GTPase
-
Saccharomyces cerevisiae