Any feedback?
Literature summary for 3.6.5.3 extracted from
- EF-Tu, a GTPase odyssey (1998), Biochim. Biophys. Acta, 1443, 1-22.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| kirromycin | - |
Salmonella enterica subsp. enterica serovar Typhimurium |  |
| kirromycin | - |
Thermus aquaticus | |
| kirromycin | - |
Thermus thermophilus | |
| kirromycin | - |
Escherichia coli | |
| ribosomal subunits | - |
Escherichia coli | |
| ribosomal subunits | - |
Pseudomonas fluorescens |
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | chaperon-activity | Salmonella enterica subsp. enterica serovar Typhimurium |
| medicine | chaperon-activity | Thermus aquaticus |
| medicine | chaperon-activity | Thermus thermophilus |
| medicine | chaperon-activity | Escherichia coli |
| medicine | protein biosynthesis | Salmonella enterica subsp. enterica serovar Typhimurium |
| medicine | protein biosynthesis | Thermus aquaticus |
| medicine | protein biosynthesis | Thermus thermophilus |
| medicine | protein biosynthesis | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
- |
Escherichia coli |
- |
Streptomyces coelicolor |
- |
Streptomyces lividans |
- |
Planobispora rosea |
- |
Streptomyces collinus |
- |
Streptomyces ramocissimus |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
- |
Thermus aquaticus |
- |
Thermus thermophilus |
- |
Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| enacylotoxin IIa | - |
Escherichia coli | |
| enacylotoxin IIa | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| enacylotoxin IIa | - |
Thermus aquaticus | |
| enacylotoxin IIa | - |
Thermus thermophilus | |
| ppGpp | - |
Escherichia coli | |
| ppGpp | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| ppGpp | - |
Thermus aquaticus | |
| ppGpp | - |
Thermus thermophilus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | - |
? | - |
? | |
| GDP + H2O | Thermus aquaticus | - |
? | - |
? | |
| GDP + H2O | Thermus thermophilus | - |
? | - |
? | |
| GDP + H2O | Escherichia coli | - |
? | - |
? | |
| GTP + H2O | Salmonella enterica subsp. enterica serovar Typhimurium | - |
GDP + phosphate | - |
? | |
| GTP + H2O | Thermus aquaticus | - |
GDP + phosphate | - |
? | |
| GTP + H2O | Thermus thermophilus | - |
GDP + phosphate | - |
? | |
| GTP + H2O | Escherichia coli | - |
GDP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
elongations factor (EF)Tu | - |
| Planobispora rosea | - |
elongation factor (EF)Tu | - |
| Pseudomonas fluorescens | - |
elongation factor (EF)Tu | - |
| Salmonella enterica subsp. enterica serovar Typhimurium | - |
elongation factor (EF)Tu | - |
| Streptomyces coelicolor | - |
elongation factor (EF)Tu | - |
| Streptomyces collinus | - |
elongation factor (EF)Tu | - |
| Streptomyces lividans | - |
elongation factor (EF)Tu | - |
| Streptomyces ramocissimus | - |
elongation factor (EF)Tu | - |
| Thermus aquaticus | - |
elongation factor (EF)Tu | - |
| Thermus thermophilus | - |
elongation factor (EF)Tu | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | trypsin degradation | Salmonella enterica subsp. enterica serovar Typhimurium |
| proteolytic modification | trypsin degradation | Thermus aquaticus |
| proteolytic modification | trypsin degradation | Thermus thermophilus |
| proteolytic modification | trypsin degradation | Escherichia coli |
| side-chain modification | acetylation and methylation | Salmonella enterica subsp. enterica serovar Typhimurium |
| side-chain modification | acetylation and methylation | Thermus aquaticus |
| side-chain modification | acetylation and methylation | Thermus thermophilus |
| side-chain modification | acetylation and methylation | Escherichia coli |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Salmonella enterica subsp. enterica serovar Typhimurium |
- |
Thermus aquaticus |
- |
Thermus thermophilus |
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GDP + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
| GDP + H2O | - |
Thermus aquaticus | ? | - |
? | |
| GDP + H2O | - |
Thermus thermophilus | ? | - |
? | |
| GDP + H2O | - |
Escherichia coli | ? | - |
? | |
| GTP + H2O | - |
Salmonella enterica subsp. enterica serovar Typhimurium | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Thermus aquaticus | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Thermus thermophilus | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Escherichia coli | GDP + phosphate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
