Activating Compound | Comment | Organism | Structure |
---|---|---|---|
geranylgeranyl transferase I | RhoA is activated by geranylgeranylation, which promotes its membrane anchoring, the geranylgeranyl transferase I inhibitor GGTI-2166to is used to inhibit geranylgeranylation | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MC3T3-E1 cell | - |
Mus musculus | - |
osteoblast | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RhoA | - |
Mus musculus |