Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein. Altering the intracellular trafficking of P-glycoprotein by modulation of its small GTPase regulators can be potential strategy to overcome multidrug resistance, a major obstacle in cancer chemotherapy | GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein. Altering the intracellular trafficking of P-glycoprotein by modulation of its small GTPase regulators can be potential strategy to overcome multidrug resistance, a major obstacle in cancer chemotherapy | Homo sapiens | GDP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
small GTPases Rab5 | - |
Homo sapiens |
small GTPases Ral5 | - |
Homo sapiens |