Cloned (Comment) | Organism |
---|---|
Cdc42, expression in Escherichia coli | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | detailed kinetic study of the interaction of GTP with Cdc42 in the absence and presence of Mg2+, biphasic reaction | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | the Mg2+ cofactor acts as a stabilizer for the bound nucleotides by slowing down the off and on rates, Mg2+ has only a minor effect on the intrinsic hydrolysis rate of GTP, kinetic study of the interaction of GTP with Cdc42 in the absence and presence of Mg2+ | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
GTP + H2O = GDP + phosphate | mechanism, biphasic reaction | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
GTP + H2O | intrinsic GTPase reaction mechanism, biphasic reaction | Homo sapiens | GDP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdc42 | Rho family small GTPase | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Homo sapiens |