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Literature summary for 3.6.4.B11 extracted from

  • Kalliomaa-Sanford, A.K.; Rodriguez-Castaneda, F.A.; McLeod, B.N.; Latorre-Rosello, V.; Smith, J.H.; Reimann, J.; Albers, S.V.; Barilla, D.
    Chromosome segregation in Archaea mediated by a hybrid DNA partition machine (2012), Proc. Natl. Acad. Sci. USA, 109, 3754-3759.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.4.B11

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q981B3
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Saccharolobus solfataricus P2 Q981B3
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-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharolobus solfataricus

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O = ADP + phosphate + phosphate cytoskeleton-based apparatus to drive chromosome segregation consisting of two interacting proteins, SegA and SegB. SegA is an ATPase that polymerizes in vitro and SegB is a site-specific DNA-binding protein contacting palindromic sequences located upstream of the segAB cassette. SegB interacts with SegA in the presence of nucleotides and dramatically affects its polymerization dynamics. SegB strongly stimulates SegA polymerization, possibly by promoting SegA nucleation and accelerating polymer growth. The SegAB complex fulfills a crucial function in chromosome segregation Saccharolobus solfataricus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O cytoskeleton-based apparatus to drive chromosome segregation consisting of two interacting proteins, SegA and SegB. SegA is an ATPase that polymerizes in vitro and that SegB is a site-specific DNA-binding protein contacting palindromic sequences located upstream of the segAB cassette. SegB interacts with SegA in the presence of nucleotides and dramatically affects its polymerization dynamics. SegB strongly stimulates SegA polymerization, possibly by promoting SegA nucleation and accelerating polymer growth. The SegAB complex fulfills a crucial function in chromosome segregation Saccharolobus solfataricus ADP + phosphate + phosphate
-
 ?
ATP + H2O cytoskeleton-based apparatus to drive chromosome segregation consisting of two interacting proteins, SegA and SegB. SegA is an ATPase that polymerizes in vitro and that SegB is a site-specific DNA-binding protein contacting palindromic sequences located upstream of the segAB cassette. SegB interacts with SegA in the presence of nucleotides and dramatically affects its polymerization dynamics. SegB strongly stimulates SegA polymerization, possibly by promoting SegA nucleation and accelerating polymer growth. The SegAB complex fulfills a crucial function in chromosome segregation Saccharolobus solfataricus P2 ADP + phosphate + phosphate
-
 ?

Subunits

Subunits Comment Organism
polymer in vitro SegA assembles into polymers Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
SegA
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 Saccharolobus solfataricus
SSO0034 locus name Saccharolobus solfataricus