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Literature summary for 3.6.4.B1 extracted from
- MS-KIF18A, a kinesin, is associated with estrogen receptor (2006), J. Cell. Biochem., 100, 693-702.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in mesenchymal marrow cells and COS-7 cells, as green fluorescent protein fusion protein | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
| cytosol | - |
Homo sapiens | 5829 | - |
| nucleus | - |
Mus musculus | 5634 | - |
| nucleus | - |
Homo sapiens | 5634 | - |
| plasma membrane | - |
Mus musculus | 5886 | - |
| plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Mus musculus | interactions between MS-KIF18A, ERalpha and caveolin-1 are involved in the estrogen non-genomic response and the activation of the ERK pathway in MBA-15 cells | ADP + phosphate | - |
? |  |
| additional information | Mus musculus | role for KIF18A and estrogen receptor alpha in a non-genomic response of MBA-15 cells challenged with 17beta-estrogen | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| marrow cell | mesenchymal marrow cell | Homo sapiens | - |
| MBA-15 cell | - |
Mus musculus | - |
| MBA-15 cell | marrow stromal cell line | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | interactions between MS-KIF18A, ERalpha and caveolin-1 are involved in the estrogen non-genomic response and the activation of the ERK pathway in MBA-15 cells | Mus musculus | ADP + phosphate | - |
? | |
| additional information | role for KIF18A and estrogen receptor alpha in a non-genomic response of MBA-15 cells challenged with 17beta-estrogen | Mus musculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | interaction of KIF18A with estrogen receptor ERalpha | Mus musculus |
| More | interaction of KIF18A with estrogen receptor ERalpha | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| KIF18A | - |
Mus musculus |
| KIF18A | - |
Homo sapiens |
| MS-KIF18A | - |
Mus musculus |
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Release 2023.1 (January 2023)
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