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Literature summary for 3.6.4.7 extracted from
- ATP-driven processes of peroxisomal matrix protein import (2017), Biol. Chem., 398, 607-624 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | the Pex1p/Pex6p complex exhibits a dual localization, with one fraction anchored to the peroxisomal membrane by its interaction to Pex15p and the second fraction located in the cytosol | Saccharomyces cerevisiae | 5829 | - |
| peroxisomal membrane | the Pex1p/Pex6p complex exhibits a dual localization, with one fraction anchored to the peroxisomal membrane by its interaction to Pex15p and the second fraction located in the cytosol | Saccharomyces cerevisiae | 5778 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | Saccharomyces cerevisiae | - |
ADP + phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O | - |
Saccharomyces cerevisiae | ADP + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterohexamer | the ATPases Pex1p and Pex6p represent a heterohexameric enzyme complex | Saccharomyces cerevisiae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AAA+-ATPase | - |
Saccharomyces cerevisiae |
| ATPase associated with various cellular activities | - |
Saccharomyces cerevisiae |
| Pex1p | - |
Saccharomyces cerevisiae |
| Pex6p | - |
Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the ATPases Pex1p and Pex6p form a heterohexameric complex, which is recruited to the peroxisomal import machinery by the membrane anchor protein Pex15p. The Pex1p/Pex6p complex recognizes the ubiquitinated import receptors, pulls them out of the membrane and releases them into the cytosol | Saccharomyces cerevisiae |
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