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Literature summary for 3.6.4.6 extracted from

  • Faber, K.N.; Heyman, J.A.; Subramani, S.
    Two AAA family peroxins, PpPex1p and PpPex6p, interact with each other in an ATP-dependent manner and are associated with different subcellular membranous structures distinct from peroxisomes (1998), Mol. Cell. Biol., 18, 936-943.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine diagnosis, HsPex6p mutations are one of the causes of Zellweger syndrome Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Komagataella pastoris 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
320000 400000 heterodimeric PpPex1p-PpPex6p complex Komagataella pastoris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
ADP + phosphate
-
?
ATP + H2O Komagataella pastoris
-
ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Komagataella pastoris
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Komagataella pastoris

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Homo sapiens
ATP + H2O = ADP + phosphate large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger 's syndrome. Komagataella pastoris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Homo sapiens ADP + phosphate
-
?
ATP + H2O
-
Komagataella pastoris ADP + phosphate
-
?

Synonyms

Synonyms Comment Organism
HsPex6p
-
Homo sapiens
PpPex1p
-
Komagataella pastoris
PpPex6p
-
Komagataella pastoris