Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Tetragenococcus halophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Tetragenococcus halophilus | enzyme forms dimers and monomers to function as a holding chaperone under stress conditions, whereas it forms a hexamer ring to function as a chaperone in cooperation with KJE and ATP under poststress conditions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tetragenococcus halophilus | - |
isoform ClpB | - |
Purification (Comment) | Organism |
---|---|
recombinant protein | Tetragenococcus halophilus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme forms dimers and monomers to function as a holding chaperone under stress conditions, whereas it forms a hexamer ring to function as a chaperone in cooperation with KJE and ATP under poststress conditions | Tetragenococcus halophilus | ? | - |
? | |
additional information | the hexameric, nonstress form of ClpB reactivates heat-aggregated proteins dependent on the DnaK system and ATP. The mixture of dimer and monomer, which is formed under stress conditions, protects substrate proteins from thermal inacivation and aggregation | Tetragenococcus halophilus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | and monomer, under stress conditions such as temperature above 45°C, or more than 1 M KCl, electron microscopy | Tetragenococcus halophilus |
hexamer | in presence of ATP, under nonstress conditions, electron microscopy | Tetragenococcus halophilus |
monomer | and dimer, under stress conditions such as temperature above 45°C, or more than 1 M KCl, electron microscopy | Tetragenococcus halophilus |