Protein Variants | Comment | Organism |
---|---|---|
additional information | identification of 25 mutations within the two major cytosolic Hsp70-SSa molecular chaperones that impair the propagation of the [PSI+] prion. All but one mutation are located within the ATPase domain, and only mutation SSA2-A176T has major effects on growth rate | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | regulation of Hsp70 Ssa chaperone ATP hydrolysis is involved in prion propagation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
isoform Hsp70 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | regulation of Hsp70 Ssa chaperone ATP hydrolysis is involved in prion propagation | Saccharomyces cerevisiae | ? | - |
? |