Crystallization (Comment) | Organism |
---|---|
41.9-kDa human Hsp70 ATPase domain | Homo sapiens |
44-kDa wild-type Hsc70 ATPase fragment | Bos taurus |
DnaK | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
44000 | - |
- |
Bos taurus |
44000 | - |
N-terminal domain | Homo sapiens |
70000 | - |
- |
Escherichia coli |
70000 | - |
- |
Homo sapiens |
70000 | - |
- |
Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Escherichia coli | - |
ADP + phosphate | - |
? | |
ATP + H2O | Homo sapiens | - |
ADP + phosphate | - |
? | |
ATP + H2O | Bos taurus | - |
ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Escherichia coli | - |
- |
- |
Homo sapiens | - |
human | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Escherichia coli | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Homo sapiens | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Escherichia coli | ADP + phosphate | - |
? | |
ATP + H2O | - |
Homo sapiens | ADP + phosphate | - |
? | |
ATP + H2O | - |
Bos taurus | ADP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Escherichia coli |
dimer | - |
Homo sapiens |
dimer | - |
Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
bATPase | - |
Bos taurus |
BiP | - |
Bos taurus |
Grp78 | - |
Bos taurus |
hATPase | - |
Homo sapiens |
Hsc70 | - |
Bos taurus |
human Hsp70 molecular chaperone | - |
Homo sapiens |