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Literature summary for 3.6.1.8 extracted from

  • Capito, K.; Hansen, S.E.; Hedeskov, C.J.; Thams, D.
    Presence of ATP-pyrophosphohydrolase in mouse pancreatic islets (1986), Diabetes, 35, 1096-1100.
    View publication on PubMed
Search for more literature for 3.6.1.8

Activating Compound

Activating Compound Comment Organism Structure
3-isobutyl-1-methylxanthine activation in preincubation Mus musculus
cAMP weak activation Mus musculus
glucose activation in preincubation Mus musculus
NaF 20 mM Mus musculus
NaN3 10 mM Mus musculus
oleic acid
-
 Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
phosphatidylserine
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.076
-
 ATP in presence of ZnCl2 and CaCl2 Mus musculus
0.18
-
 ATP in presence of 2 mM ZnCl2 Mus musculus
0.2
-
 ATP without added metal ions Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Ba2+ no effect Mus musculus
Ca2+ required for activity Mus musculus
Co2+ activating Mus musculus
Mg2+ no effect Mus musculus
Mn2+ no effect Mus musculus
Sr2+ no effect Mus musculus
Zn2+ activating Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Mus musculus
-
 AMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreatic islet
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Mus musculus AMP + diphosphate
-
 ?