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Literature summary for 3.6.1.7 extracted from

  • Bemporad, F.; Gsponer, J.; Hopearuoho, H.I.; Plakoutsi, G.; Stati, G.; Stefani, M.; Taddei, N.; Vendruscolo, M.; Chiti, F.
    Biological function in a non-native partially folded state of a protein (2008), EMBO J., 27, 1525-1535.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.7

Protein Variants

Protein Variants Comment Organism
A18G site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
A37G site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
A46G site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states Saccharolobus solfataricus
A46G site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
A58G site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
E59A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
F29L site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
F88A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
F98L site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
G52A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
G52A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
G93A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
I42V site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
I72V site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
K92A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
K92A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
L49A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
L65A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states Saccharolobus solfataricus
L65A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
L68A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
M16A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
N48A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
P50A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
P76A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
P77A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
R15A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
R19A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
R30A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
R71A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
S89A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
V20A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states Saccharolobus solfataricus
V20A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
V24A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
V27A site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme both in native an partially unfolded states, thermodynamic and kinetic parameters Saccharolobus solfataricus
V54A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
V81A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
V84A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
Y61A site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus
Y61L site-directed mutagenesis, thermodynamic and kinetic parameters Saccharolobus solfataricus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information thermodynamic and kinetic parameters Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the partially folded ensemble of AcP displays enzymatic activity, but the early enzymatic activity of AcP is not contributed by the unfolded or native states Saccharolobus solfataricus ?
-
 ?

Subunits

Subunits Comment Organism
More The partially folded ensemble of AcP displays enzymatic activity Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
ACP
-
 Saccharolobus solfataricus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Saccharolobus solfataricus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
 assay at Saccharolobus solfataricus