Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus C57BL/6 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | - |
Mus musculus | - |
esophagus | while all cell layers of the esophagus express NTPDase3, NTPDase3 localization in the forestomach is limited to the basal cell layer | Mus musculus | - |
gastrointestinal tract | NTPDase3 in cells from the stratified esophageal and forestomach epithelia, and in some enteroendocrine cells of the gastric antrum. NTPDase3 and -2 are coexpressed within the myenteric and submucosal plexuses, as well as in the nerve terminals of the smooth muscle layer and mucosa | Mus musculus | - |
additional information | specific localization of NTPDase3 in the digestive system, by semiquantitative RT-PCR, immunohistochemistry, and in situ activity assay, detailed overview | Mus musculus | - |
pancreas | - |
Mus musculus | - |
pancreatic acinar cell | - |
Mus musculus | - |
parotid gland | serous acinar cells of parotid glands | Mus musculus | - |
salivary gland | NTPDase3 in epithelial cells in serous acini of salivary glands and mucous acini and duct cells of sublingual salivary glands | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
ecto-ATPase | - |
Mus musculus |
NTPDase3 | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | the mean glial Ca2+ response to ATP was significantly larger in the presence of an NTPDase inhibitor | Mus musculus |
physiological function | functional roles of NTPDase3 in association with NTPDase2 and ecto-5'-nucleotidase, in epithelial functions such as secretion and in enteric neurotransmission | Mus musculus |