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Literature summary for 3.6.1.6 extracted from

  • Uccelletti, D.; OCallaghan, C.; Berninsone, P.; Zemtseva, I.; Abeijon, C.; Hirschberg, C.B.
    ire-1-dependent transcriptional up-regulation of a lumenal uridine diphosphatase from Caenorhabditis elegans (2004), J. Biol. Chem., 279, 27390-27398.
    View publication on PubMed
Search for more literature for 3.6.1.6

Activating Compound

Activating Compound Comment Organism Structure
additional information no enzymatic activity in the presence of EDTA Caenorhabditis elegans

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae gda1-null mutant Caenorhabditis elegans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.18
-
 UDP at pH 8.0 in the presence of 10 mM Ca2+ Caenorhabditis elegans

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Caenorhabditis elegans 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 10 mM, stimulation Caenorhabditis elegans
Mg2+ 10 mM, stimulation Caenorhabditis elegans
Mn2+ 10 mM, stimulation Caenorhabditis elegans

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 strains N2 and RE666
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP + H2O
-
 Caenorhabditis elegans GMP + phosphate
-
 ?
UDP + H2O
-
 Caenorhabditis elegans UMP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
lumenal ecto-nucleoside di-phosphohydrolase
-
 Caenorhabditis elegans
lumenal uridine diphosphatase
-
 Caenorhabditis elegans
UDA-1
-
 Caenorhabditis elegans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 with GDP as substrate Caenorhabditis elegans
8
-
 with UDP as substrate Caenorhabditis elegans