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Literature summary for 3.6.1.6 extracted from
- Affinity purification and some properties of nucleoside diphosphatase from rat liver cytosol (1978), Biochim. Biophys. Acta, 525, 265-274.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 8.3 | 10 | UDP | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | increases hydrolysis of IDP | Rattus norvegicus | |
| Mg2+ | increases hydrolysis of IDP | Rattus norvegicus | |
| Mn2+ | increases hydrolysis of IDP | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
4 * 30000, SDS-PAGE | Rattus norvegicus |
| 120000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Rattus norvegicus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| affinity purification | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 36.9 | - |
- |
Rattus norvegicus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C, stable for several weeks | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + H2O | weak activity | Rattus norvegicus | AMP + phosphate | - |
? | |
| CDP + H2O | weak activity | Rattus norvegicus | CMP + phosphate | - |
? | |
| GDP + H2O | - |
Rattus norvegicus | GMP + phosphate | - |
? | |
| IDP + H2O | - |
Rattus norvegicus | IMP + phosphate | - |
? | |
| UDP + H2O | - |
Rattus norvegicus | UMP + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 30000, SDS-PAGE | Rattus norvegicus |
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Release 2023.1 (January 2023)
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