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Literature summary for 3.6.1.6 extracted from
- Immobilization of nucleoside diphosphatase at its allosteric site using immobilized derivatives of pyridoxal 5 -phosphate (1980), Arch. Biochem. Biophys., 204, 326-330.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | 0.2 mM ATP stimulates free enzyme 2.6fold when IDP is used as substrate, immobilized enzyme on CNBr-activated Sepharose is activated almost to the same degree, the immobilized enzyme on the 3-O-pyridoxal 5'-phosphate-Sepharose is less sensitive to ATP | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| IDP + H2O | - |
Rattus norvegicus | IMP + phosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 38 | - |
free enzyme | Rattus norvegicus |
| 50 | - |
immobilized enzyme | Rattus norvegicus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
5 min, immobilized enzyme is stable, free enzyme loses about 90% of its activity | Rattus norvegicus |
| 55 | - |
5 min, about 50% loss of activity of the immobilized enzyme, complete loss of activity of the free enzyme | Rattus norvegicus |
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