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Literature summary for 3.6.1.6 extracted from

  • Ohkubo, I.; Ishibashi, T.; Taniguchi, N.; Makita, A.
    Purification and characterization of nucleoside diphosphatase from rat-liver microsomes. Evidence for metalloenzyme and glycoprotein (1980), Eur. J. Biochem., 112, 111-118.
    View publication on PubMed
Search for more literature for 3.6.1.6

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 2 mM, 66% inhibition Rattus norvegicus
2,2'-bipyridyl 2 mM, 64% inhibition Rattus norvegicus
EDTA 0.1 mM, complete inhibition Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5
-
 UDP
-
 Rattus norvegicus
3.5
-
 IDP
-
 Rattus norvegicus
4
-
 GDP
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ stimulates Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
65000
-
 2 * 65000, SDS-PAGE Rattus norvegicus
130000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein contains 9% carbohydrate Rattus norvegicus

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP + H2O
-
 Rattus norvegicus GMP + phosphate
-
 ?
IDP + H2O
-
 Rattus norvegicus IMP + phosphate
-
 ?
UDP + H2O
-
 Rattus norvegicus UMP + phosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 65000, SDS-PAGE Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Rattus norvegicus