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BRENDA support

Literature summary for 3.6.1.56 extracted from

  • Takahashi, M.; Maraboeuf, F.; Sakai, Y.; Yakushiji, H.; Mishima, M.; Shirakawa, M.; Iwai, S.; Hayakawa, H.; Sekiguchi, M.; Nakabeppu, Y.
    Role of tryptophan residues in the recognition of mutagenic oxidized nucleotides by human antimutator MTH1 protein (2002), J. Mol. Biol., 319, 129-139.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
W117A the fluorescence of the modified protein is weaker than that of wild-type MTH1. The modified protein exhibits no hydrolysis of either 8-oxo-dGTP or 2-hydroxy-dATP Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P36639
-
-

Synonyms

Synonyms Comment Organism
MTH1
-
Homo sapiens