Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | excitotoxicity initiated by kainate administration results in an increase ofMTH1protein expression in the mouse hippocampus | Mus musculus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | MTH1 efficiently suppresses the accumulation of 8-oxoguanine in both cellular DNA and RNA in the hippocampus, especially in microglia, caused by excitotoxicity (caused by the systemic administration of kainate) | Mus musculus |