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Literature summary for 3.6.1.23 extracted from
- Characterization of an early gene encoding for dUTPase in Rana grylio virus (2007), Virus Res., 123, 128-137.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene DUT, DNA and amino acid sequence determination and analysis, phylogenetic analysis, temporal expression pattern during the viral infection course, overexpression as EGFP-fusion enzyme in the cytoplasm of EPC cells, no effects on virus replication by enzyme overexpression, overview | Rana grylio iridovirus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Rana grylio iridovirus | 5737 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 174000 | - |
x * 174000, about, amino acid sequence calculation | Rana grylio iridovirus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dUTP + H2O | Rana grylio iridovirus | the enzyme regulates the levels of dUTP | dUMP + diphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rana grylio iridovirus | - |
RGV, an iridovirus pathogenic in the pig frog | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | temporal expression pattern during the viral infection course, DUT is an early viral gene, overview | Rana grylio iridovirus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dUTP + H2O | - |
Rana grylio iridovirus | dUMP + diphosphate | - |
? | |
| dUTP + H2O | the enzyme regulates the levels of dUTP | Rana grylio iridovirus | dUMP + diphosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 174000, about, amino acid sequence calculation | Rana grylio iridovirus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DUT | - |
Rana grylio iridovirus |
| dUTPase | - |
Rana grylio iridovirus |
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Release 2023.1 (January 2023)
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