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Literature summary for 3.6.1.23 extracted from
- Characterization of a herpes simplex virus type 2 deoxyuridine triphosphate nucleotidohydrolase and mapping of a gene conferring type specificity for the enzyme (1987), Virology, 156, 282-292.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ag+ | - |
Human alphaherpesvirus 2 |  |
| Cu2+ | - |
Human alphaherpesvirus 2 | |
| EDTA | reversed by Co2+ or Mg2+ | Human alphaherpesvirus 2 | |
| Hg+ | - |
Human alphaherpesvirus 2 | |
| Hg2+ | - |
Human alphaherpesvirus 2 | |
| Pb2+ | - |
Human alphaherpesvirus 2 | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0036 | - |
dUTP | - |
Human alphaherpesvirus 2 | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human alphaherpesvirus 2 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Human alphaherpesvirus 2 |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Human alphaherpesvirus 2 |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dUTP + H2O | - |
Human alphaherpesvirus 2 | dUMP + diphosphate | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 42 | - |
t1/2: 18 min, in presence of 2 mM 2-mercaptoethaol | Human alphaherpesvirus 2 |
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