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Literature summary for 3.6.1.22 extracted from

  • Davies, R.; King, H.K.
    An enzyme degrading reduced nicotinamide-adenine dinucleotide in Proteus vulgaris (1978), Biochem. J., 175, 669-674.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.22

Activating Compound

Activating Compound Comment Organism Structure
Urea 8 M urea, 30 mM Phosphate buffer, pH 7.4, 100% activation Proteus vulgaris

Inhibitors

Inhibitors Comment Organism Structure
Al3+
-
 Proteus vulgaris
Ba2+
-
 Proteus vulgaris
Cr2+
-
 Proteus vulgaris
Fe2+
-
 Proteus vulgaris
Sn2+
-
 Proteus vulgaris

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ necessary for maximum activity Proteus vulgaris
Mg2+ strong activation at concentration of 0.4 mM Proteus vulgaris
Mn2+ strong activation at concentration of 0.4 mM Proteus vulgaris
Ni2+ strong activation at concentration of 0.4 mM Proteus vulgaris

Organism

Organism UniProt Comment Textmining
Proteus vulgaris
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Proteus vulgaris

Storage Stability

Storage Stability Organism
18°C, 50 mM phosphate buffer, pH 7.0, 1 h, 70% loss of activity Proteus vulgaris
4°C, 50 mM phosphate buffer, pH 7.0, overnight, 70% loss of activity Proteus vulgaris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + H2O
-
 Proteus vulgaris NMN + AMP
-
 ir

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
73
-
 2 min causes activation Proteus vulgaris
98
-
 few min at 98°C causes loss of activity, 30 s causes activation Proteus vulgaris