Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,4-dihydroxy-5,8-bis[(4-methylphenyl)amino]anthracene-9,10-dione | NSC86169 | Lupinus angustifolius | |
2-((8-hydroxy-4-(4-methyl-2-sulfoanilino)-9,10-dioxo-9,10-dihydro-1-anthracenyl)amino)-5-methylbenzenesulfonic acid | NSC51531, competitive inhibitor | Lupinus angustifolius | |
2-[2-[(4-aminophenyl)amino]-6-phenylpyrimidin-4-yl]phenol | NSC232476 | Lupinus angustifolius | |
5-hydroxy-1,4-bis[(4-methylphenyl)amino]anthracene-9,10-dione | NSC300513 | Lupinus angustifolius | |
5-methyl-2-[[4-(methylamino)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino]benzenesulfonate | NSC401611 | Lupinus angustifolius | |
additional information | NSC113427, NSC133815, and NSC305522, do not exhibit any enzyme inhibition at concentrations in excess of 0.1 mM | Lupinus angustifolius | |
perylene-3,4,9,10-tetracarboxylic acid | NSC89768 | Lupinus angustifolius |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lupinus angustifolius | O04841 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | - |
Lupinus angustifolius | ATP + AMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ap4A hydrolase | - |
Lupinus angustifolius |
diadenosine 5,5-P1,P4-tetraphosphate hydrolase | - |
Lupinus angustifolius |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00109 | - |
2-((8-hydroxy-4-(4-methyl-2-sulfoanilino)-9,10-dioxo-9,10-dihydro-1-anthracenyl)amino)-5-methylbenzenesulfonic acid | in 100 mM Tris-acetate, pH 7.7, 5 mM magnesium acetate, and 5% DMSO, at 25°C | Lupinus angustifolius | |
0.00289 | - |
5-methyl-2-[[4-(methylamino)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino]benzenesulfonate | in 100 mM Tris-acetate, pH 7.7, 5 mM magnesium acetate, and 5% (v/v) DMSO, at 25°C | Lupinus angustifolius | |
0.005 | - |
2-[2-[(4-aminophenyl)amino]-6-phenylpyrimidin-4-yl]phenol | Ki about 0.005 mM, in 100 mM Tris-acetate, pH 7.7, 5 mM magnesium acetate, and 5% (v/v) DMSO, at 25°C | Lupinus angustifolius |