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Literature summary for 3.5.4.B9 extracted from

  • Zhu, Y.P.; Peng, Z.G.; Wu, Z.Y.; Li, J.R.; Huang, M.H.; Si, S.Y.; Jiang, J.D.
    Host APOBEC3G protein inhibits HCV replication through direct binding at NS3 (2015), PLoS ONE, 10, e0121608.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytosine in single-stranded viral DNA + H2O Homo sapiens
-
uracil in single-stranded viral DNA + NH3
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9HC16
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Huh-7.5 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytosine in single-stranded viral DNA + H2O
-
Homo sapiens uracil in single-stranded viral DNA + NH3
-
?

Synonyms

Synonyms Comment Organism
A3G
-
Homo sapiens
APOBEC3G
-
Homo sapiens

General Information

General Information Comment Organism
physiological function APOBEC3G protein inhibits HCV replication through direct binding at non-structural protein NS3 at its C-terminus, which is responsible for NS3's helicase and NTPase activities Homo sapiens