KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
5,10-methenyltetrahydrofolate | - |
Oryctolagus cuniculus | |
0.074 | - |
5,10-methenyltetrahydrofolate | - |
Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methenyltetrahydrofolate + H2O | Cavia porcellus | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Mus musculus | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Homo sapiens | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Rattus norvegicus | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Sus scrofa | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Bos taurus | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Oryctolagus cuniculus | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Ovis aries | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Pseudomonas fluorescens | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Clostridium cylindrosporum | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Gottschalkia acidurici | - |
10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | Felis sp. | - |
10-formyltetrahydrofolate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
beef | - |
Cavia porcellus | - |
guinea-pig | - |
Clostridium cylindrosporum | - |
- |
- |
Felis sp. | - |
cat | - |
Gottschalkia acidurici | - |
- |
- |
Homo sapiens | - |
human, bifunctional mitochondrial enzyme, trifunctional cytoplasmic enzyme | - |
Mus musculus | - |
mouse, bifunctional mitochondrial enzyme | - |
Oryctolagus cuniculus | - |
rabbit | - |
Ovis aries | - |
- |
- |
Pseudomonas fluorescens | - |
ATCC 11299 | - |
Rattus norvegicus | - |
rat, trifunctional cytoplasmic enzyme | - |
Sus scrofa | - |
pig, trifunctional enzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Cavia porcellus | - |
kidney | - |
Mus musculus | - |
kidney | - |
Rattus norvegicus | - |
kidney | - |
Sus scrofa | - |
kidney | - |
Bos taurus | - |
kidney | - |
Oryctolagus cuniculus | - |
kidney | - |
Ovis aries | - |
kidney | - |
Felis sp. | - |
liver | - |
Cavia porcellus | - |
liver | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Sus scrofa | - |
liver | - |
Bos taurus | - |
liver | - |
Oryctolagus cuniculus | - |
liver | - |
Ovis aries | - |
liver | - |
Felis sp. | - |
spleen | - |
Cavia porcellus | - |
spleen | - |
Mus musculus | - |
spleen | - |
Rattus norvegicus | - |
spleen | - |
Oryctolagus cuniculus | - |
spleen | - |
Felis sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.09 | - |
source spleen | Oryctolagus cuniculus |
0.1 | - |
source spleen | Cavia porcellus |
0.1 | - |
source kidney | Ovis aries |
0.13 | - |
source kidney | Bos taurus |
0.14 | - |
- |
Homo sapiens |
0.14 | - |
- |
Ovis aries |
0.16 | - |
source spleen | Mus musculus |
0.18 | - |
source liver | Rattus norvegicus |
0.22 | - |
source liver | Sus scrofa |
0.23 | - |
- |
Rattus norvegicus |
0.23 | - |
source spleen | Felis sp. |
0.25 | - |
source kidney | Oryctolagus cuniculus |
0.27 | - |
source liver | Felis sp. |
0.29 | - |
- |
Pseudomonas fluorescens |
0.35 | - |
source kidney | Cavia porcellus |
0.36 | - |
source kidney | Rattus norvegicus |
0.4 | - |
source liver | Mus musculus |
0.41 | - |
source kidney | Felis sp. |
0.5 | - |
source kidney | Mus musculus |
0.65 | - |
- |
Bos taurus |
0.82 | - |
source liver | Oryctolagus cuniculus |
1.04 | - |
source liver | Cavia porcellus |
2.2 | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-20°C, loses 15% activity in 1 day, 50% in 5 days and 70% in 30 days | Sus scrofa |
0°C, relatively unstable, losing 40% activity in 1 day and 75% in 4 days | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methenyltetrahydrofolate + H2O | - |
Cavia porcellus | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Mus musculus | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Homo sapiens | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Rattus norvegicus | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Sus scrofa | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Bos taurus | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Oryctolagus cuniculus | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Ovis aries | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Pseudomonas fluorescens | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Clostridium cylindrosporum | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Gottschalkia acidurici | 10-formyltetrahydrofolate | - |
? | |
5,10-methenyltetrahydrofolate + H2O | - |
Felis sp. | 10-formyltetrahydrofolate | - |
? |