Literature summary for 3.5.4.6 extracted from

Swieca, A.; Rybakowska, I.; Milczarek, R.; Klimek, J.; Kaletha, K.
AMP-deaminase from developing human placenta (2010), Placenta, 31, 460-462.

Search for more literature for 3.5.4.6

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
68000	-	SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
placenta	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.01	-	enzyme from 40th week-old placenta, in 0.1 M succinate buffer, pH 6.5, at 5 mM substrate (AMP) concentration, at 30°C	Homo sapiens
0.025	-	enzyme from 33rd week-old placenta, in 0.1 M succinate buffer, pH 6.5, at 5 mM substrate (AMP) concentration, at 30°C	Homo sapiens
0.037	-	enzyme from 25th week-old placenta, in 0.1 M succinate buffer, pH 6.5, at 5 mM substrate (AMP) concentration, at 30°C	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
AMP + H2O	-	Homo sapiens	IMP + NH3	-	ir

Synonyms

Synonyms	Comment	Organism
AMP-deaminase	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	during pregnancy the activity of AMP-deaminase in developing human placenta gradually decreases, being in homogenates of mature, term placenta (about 40 weeks of gestation) one fourth to one third of that in homogenates of immature (about 25 weeks of gestation) organ	down

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Release 2023.1 (January 2023)