Literature summary for 3.5.4.6 extracted from

Lian, C.; Harkness, D.R.
The kinetic properties of adenylate deaminase from human erythrocytes (1978), Biochim. Biophys. Acta, 341, 27-40.

Search for more literature for 3.5.4.6

Activating Compound

Activating Compound	Comment	Organism	Structure
ADP	activates	Homo sapiens
ATP	activates	Homo sapiens
dATP	activates	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
2'-AMP	in the absence of ATP	Homo sapiens
2,3-diphosphoglyceric acid	ATP counteracts inhibition	Homo sapiens
3'-AMP	in the absence of ATP	Homo sapiens
5'-IMP	in the absence of ATP	Homo sapiens
Br-	-	Homo sapiens
Cl-	-	Homo sapiens
F-	-	Homo sapiens
I-	-	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cs+	activates	Homo sapiens
K+	activates	Homo sapiens
Li+	activates	Homo sapiens
Na+	activates	Homo sapiens
Rb+	activates	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
5.7	-	-	Homo sapiens

Storage Stability

Storage Stability	Organism
-20°C, 4 months, less than 10% loss of activity	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
AMP + H2O	-	Homo sapiens	IMP + NH3	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
additional information	-	-	Homo sapiens

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Release 2023.1 (January 2023)