Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-fluoro-D,L-tryptophan | adenosine analogue, induces conformational changes inhibiting the enzyme, structural mechanism, overview | Mus musculus | |
adenosine analogues | induce conformational changes inhibiting the enzyme, structural mechanism, overview | Mus musculus | |
additional information | loss of activity precedes the global secondary and tertiary structure transition when the enzyme is exposed to denaturant, structural mechanism, overview | Mus musculus | |
purine riboside | adenosine analogue, induces conformational changes inhibiting the enzyme, structural mechanism, overview | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | thermodynamics and kinetics | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc-metalloenzyme, binding structure | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + H2O | Mus musculus | the enzyme is crucial for purine metabolism and normal immune competence | inosine + NH3 | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P03958 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + H2O | - |
Mus musculus | inosine + NH3 | - |
ir | |
adenosine + H2O | the enzyme is crucial for purine metabolism and normal immune competence | Mus musculus | inosine + NH3 | - |
ir |
Subunits | Comment | Organism |
---|---|---|
More | the enzyme has (beta/alpha)8-barrel structure with bound zinc | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
ADA | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |